Empyema is the presence of gross pus in the pleural cavity; it consists of an effusion containing polymorphonuclear leukocytes and fibrin.The pleural space is actually a potential space created by the visceral and parietal pleura. It normally contains a scant amount of fluid which facilitates movement of the lung with the diaphragm and chest wall. Several mechanisms contribute to the development of an effusion. Pleural fluid can accumulate when alterations in hydrostatic and oncotic pressure accompany cardiac, renal, hepatic or metabolic disease, or when there are changes in pleural fluid permeability secondary to inflammation, infection, toxin, malignancy or trauma.
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